June 13, 2024

Health Supplements

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18 Best Energy Supplements for Chronic Fatigue in 2024

10 min read

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Do you suffer from chronic fatigue? If so, you are not alone. Chronic fatigue syndrome is a real condition that affects many people. There is no one-size-fits-all cure for chronic fatigue, but there are a number of energy supplements that can help. In this article, we will discuss the 18 best energy supplements for chronic fatigue in 2022. We will also provide tips on how to choose the right supplement for you. So read on to learn more!

18 Best Energy Supplements for Chronic Fatigue in 2022

  1. Elm & Rye Nootropics 

  2. Penguin CBD Oil

  3. Everest CBD Gummies

  4. Testoprime Instant Energy

  5. BATCH Brain Boost Mushroom Gummies

  6. mindbodygreen focus+

  7. Honey Gardens Premier One – Raw Energy Extreme – Caffeine Free

  8. Hum Nutrition Uber Energy

  9. Mtn Ops Ignite Energy Booster Supplements in Trail Packs

  10. Swanson Pure Energy Trial Size 14 Veg Caps

  11. Olly Daily Energy, Gummies, Tropical Passion

  12. AG1 by Athletic Greens Travel Packs

  13. Snap Metabolism and Natural Energy Supplements for Fatigue

  14. Care/of – Essential Vitamins for Energy

  15. Extreme Energy – Energy Pills That Work

  16. Super Fuel Natural Energy + Vitamin Drink

  17. Bare Performance Nutrition Strong Reds Strawberry

  18. Obvi Hello | Goodbye All Day Energy + Hormonal Balance Capsules

What are the signs of chronic fatigue? 

Chronic fatigue is a condition characterized by persistent feelings of tiredness and lack of energy. Symptoms can vary from person to person but may include muscle pain, difficulty sleeping, trouble concentrating, dizziness, nausea, and cognitive impairment.

If you are experiencing chronic fatigue, there are many different supplements that can help restore your energy levels and alleviate your symptoms.

B-complex vitamins. 

B-complex vitamins are a group of essential nutrients that play an important role in the production of energy within the body. They work together to help break down macronutrients like carbohydrates, fats, and proteins into usable energy that can fuel the body. Studies have shown that B-complex supplements can be effective in reducing fatigue and improving cognitive function in people with chronic fatigue syndrome (CFS).

Omega-3 fatty acids. 

Omega-3 fatty acids are a type of polyunsaturated fat that is important for the health of your brain and nervous system. Research has shown that they can help reduce inflammation in the body, which may be a cause of chronic fatigue. Some studies have also found that omega-3 fatty acids may be beneficial for improving mood and reducing symptoms of depression, both of which are often associated with CFS.


Caffeine is a natural stimulant found in coffee, tea, and other common beverages. It works by blocking adenosine receptors in the brain to increase levels of the neurotransmitter norepinephrine, which can help boost energy and improve alertness. Several studies have found that caffeine can be effective in reducing fatigue and increasing energy levels in people with CFS.


Ginseng is a supplement derived from the herb Panax ginseng, which has been used for centuries as a natural remedy for improving energy levels and promoting overall health. Research suggests that ginseng may help strengthen the body’s immune system and reduce inflammation. One study found that people with CFS who took ginseng showed significant improvements in energy levels, fatigue severity score, and quality of life over a six-month period compared to those who did not take the supplement.

In addition to these supplements, there are many other natural remedies that can help fight chronic fatigue and restore your energy levels. For example, getting enough sleep and exercise, eating a healthy diet, reducing stress and anxiety, and practicing mindfulness meditation can all be effective strategies for managing CFS. 

What causes chronic fatigue?

The exact cause of chronic fatigue syndrome is not fully understood, but there are several factors that are believed to play a role. These include genetics, hormonal imbalances, infections, stress and anxiety, poor diet and nutrition, sleep deprivation, and environmental toxins. 

Additionally, some evidence suggests that abnormalities in brain chemistry and the immune system may be involved in the development of CFS. For example, some studies have found that people with CFS tend to have increased levels of oxidative stress and inflammation, as well as imbalances in certain neurotransmitters like serotonin and dopamine. 

Can nootropics help with chronic fatigue? 

Nootropics are supplements that have been shown to help with a variety of cognitive functions, including energy levels. Some nootropics that may be helpful for chronic fatigue include caffeine, piracetam, and Rhodiola rosea. 

Caffeine is a stimulant that can help to increase energy levels and improve focus, while piracetam is a cognitive enhancer that can help to reduce brain fog and improve cognitive performance. Rhodiola rosea is an adaptogen herb that has been shown to help improve energy levels and reduce stress levels.

Another good supplement to consider for the best energy supplements for chronic fatigue includes CBD. CBD is also known for its energizing properties. CBD is a non-psychotropic compound found in cannabis that does not produce the “high” associated with marijuana. CBD has been shown to help improve energy levels, reduce anxiety and stress, and improve sleep quality.

What is the strongest vitamin for energy?

There is no single “strongest vitamin” that is universally effective for everyone with chronic fatigue. However, some vitamins and supplements have been shown to be particularly beneficial for reducing fatigue and improving energy levels. These include B-complex vitamins, omega-3 fatty acids, caffeine, and ginseng. 

Now that you know more about chronic fatigue, it’s time to share more details about our highly recommended 18 best energy supplements for chronic fatigue in 2022: 

Image courtesy Elm & Rye 

Nootropics are a category of medications that improve brain function. This can comprise memory, imagination, concentration, and drive. Nootropics are often taken to assist people managing ADHD, depression, or anxiety.

Our blend of ingredients can help improve cognitive function and concentration. It may be beneficial for people looking to increase alertness, productivity, and focus.

Image courtesy Penguin CBD 

We have a broad-spectrum oil available in four strengths (250mg, 600mg, 1,000mg, and 2,500mg). You can choose from five great flavors (mint, citrus, strawberry, cookies & cream, or natural). It’s always made to order which means when you buy it from us – it will be fresh!

Image courtesy Everest

Everest CBD gummies are a delicious way to get your daily dose of CBD. Made with pure, natural ingredients, these gummies are perfect for those looking for an easy and convenient way to enjoy the benefits of CBD. We only use naturally grown and high-grade hemp to make our CBD + THC gummies.

Finding supplements to deal with chronic fatigue can be challenging. But one of our favorite formulas for overcoming the ‘chronic fatigue’ challenge is TestoPrime Instant Energy. This advanced energy solution is designed for men who live challenging lives. It gives you the powerful energy boost needed to get through those difficult days with a brilliant blend of nutrients to help you increase your energy, upgrade your mental potential, and even improve your mood – all at the same time. When you just need a bit more ‘juice’ to get you through the day, TestoPrime Instant Energy may be the perfect solution.

BATCH Brain Boost Mushroom Gummies offer a unique blend of functional mushrooms and botanicals that are specifically formulated to naturally boost energy levels and enhance cognitive function. Each gummy is naturally flavored with ginger and wildberry extracts and packed with verified amounts of active compounds that are known for their exceptional support of brain and nervous system health. 

With USDA Certified Organic Lion’s Mane, Cordyceps, and Reishi mushroom extracts, these gummies help promote calm energy, sharpened focus, and reduced fatigue. BATCH is committed to providing natural health supplements that are effective and always third-party tested to ensure the highest quality product to leave you feeling productive throughout your day.

Image couretsy mindbodygreen

A capsule of mindbodygreen focus+ delivers instant energy to help you power through the afternoon slump.* It combines 150mg of plant-origin caffeine with ginseng, guarana, and vitamin B12 to improve productivity and performance.* We love that the supplement is time-released to give you sustained energy throughout the day. Plus, it also has 100mg of L-theanine per serving to promote a calm, focused energy without drowsiness.* Use code NEW15 to save 15% on your first order.

7.     Honey Gardens Premier One – Raw Energy Extreme – Caffeine Free

Image courtesy Honey Gardens 

Honey Gardens’ Premier One contains ingredients like bee pollen, propolis, green tea, acai berries and ginseng to help boost energy levels. This potent blend can be used as a daily tonic that is caffeine-free for those who are looking for natural energy support.

8.     Hum Nutrition Uber Energy

Image courtesy Hum Nutrition 

L-Tyrosine is known to increase focus and concentration, making it the perfect base for these Uber Energy capsules. These capsules are designed for busy people who want to make the most of their time and get things done. The adaptogens in these capsules help keep you focused, awake and stress-free so that you can power through your never-ending to-do list.

9.     Mtn Ops Ignite Energy Booster Supplements in Trail Packs

Image courtesy Mtn Ops 

Ignite will both refresh your body and mind . Get the full benefit from workouts by using a product that optimizes how well you perform. 900mg of Ignite’sTM brain blend, including; Choline Bitartrate, Ly-Tyrosine, Caffeine, and DMAE Bitartrate , supports cognitive function so that there is improved mental acuteness and clarity. In addition, L-Citrulline creates long-lasting Nitric Oxide release to give energy without any jitters or crashes as well  as better hydration for faster recovery time period.

10.  Swanson Pure Energy Trial Size 14 Veg Caps

Image courtesy Swanson 

Energy drinks that rely on sugar or artificial ingredients for their energy boost may give you a short-term burst of energy, but they often come with jitters, eventual fatigue (the crash!), and other unwanted side effects such as trouble sleeping or focusing. What you want—what you need—is pure energy without any strings attached.

11.  Olly Daily Energy, Gummies, Tropical Passion

Image courtesy Olly 

Olly Daily Energy gummies are designed to provide you with sustained energy throughout the day. Packed with a blend of guarana, green tea extract and B12, these gummies can help boost your mood and increase your natural energy levels without any crash or unwanted jitters.

12.  AG1 by Athletic Greens Travel Packs

Image courtesy AG1

AG1 is a daily health drink that goes beyond just greens powder, providing 75 vitamins, minerals and whole food-sourced nutrients. In addition to being a multivitamin and probiotic, AG1 also boosts energy, promotes strength and stamina while aiding in both digestion & gut health.

13.  Snap Metabolism and Natural Energy Supplements for Fatigue

Image courtesy Snap 

Our extra strength 1655mg Formula L-Arginine HCL combined with potent Herbal Extracts is a powerful product that will energize you and keep you moving throughout your day. Our unique blend of ancient herbal wisdom and modern science is sure to give you the boost you need to stay on top of your game.

Looking to boost your metabolism and lose a few pounds? This 12-plant, vitamin, and amino acid blend will help get you there. With 1000mg of L-arginine – an essential amino acid – your body will produce more nitric oxide. In turn, this helps with healthy cardiovascular circulation by delivering more oxygen to your brain, muscles, and other organs.

14.  Care/of – Essential Vitamins for Energy

Image courtesy Care/Of

Care/of is a daily multivitamin and mineral supplement that can help boost your energy and promote better focus. Packed with essential vitamins B12, C, D, E, calcium, iron, magnesium and more, these capsules provide the nutrients you need to stay focused and alert throughout the day.

15.  Extreme Energy – Energy Pills That Work

Image courtesy Extreme Energy 

Looking for an energy boost that lasts all day? Extreme Energy is a potent blend of natural stimulants and metabolism boosters designed to help you stay energized and focused, without unwanted jitters or crashes. Containing caffeine from green tea, guarana, and yerba mate, along with L-carnitine and high levels of B vitamins, this supplement will give you the boost you need without any of the side effects.

16.  Super Fuel Natural Energy + Vitamin Drink

Image courtesy Super Fuel 

If you’re looking for a healthier alternative to typical energy drinks, look no further! Our drink is fortified with plant-based caffeine, vitamins, minerals, nootropics, electrolytes, and antioxidants. It’s perfect for pre-workout or post-workout recovery, study sessions or work days when you need an extra boost of energy.

17.  Bare Performance Nutrition Strong Reds Strawberry

Image courtesy Bare Performance Nutrition 

BPN Strong Reds is a super convenient blend of ingredients equivalent to multiple servings of whole fruits and vegetables. Combined with an antioxidant and probiotic digestive enzyme blend, BPN will not only increase your energy but also improve well-being by promoting alertness, wakefulness, enhancing performance, relieving fatigue and promoting endurance. In addition, BPN will assist in digestion and nutrient absorption!

18.  Obvi Hello | Goodbye All Day Energy + Hormonal Balance Capsules

Image courtesy Obvi

Hello, With the perfect blend of B vitamins, you can normalize blood flow and sustain energy for prolonged periods in a day. Increase mental clarity all day long with this mood enhancer that contains patented ingredients proven to work. Pairs best with Goodbye for a revitalized new you free from stress, imbalanced hormones and mood fatigue.


In conclusion, chronic fatigue syndrome is a complex disorder that can have a significant impact on an individual’s quality of life. While there is no cure for the condition, several supplements can help alleviate symptoms and increase energy levels.

After conducting extensive research, we have identified the best energy supplements for chronic fatigue as rhodiola rosea, coenzyme Q10, and magnesium. These supplements have been shown to be effective in improving fatigue, mental clarity, and overall energy levels.

Rhodiola rosea is a natural adaptogen that can help combat stress and improve physical and mental performance. According to a study, rhodiola supplementation significantly improved fatigue levels and overall well-being in patients with chronic fatigue syndrome.

Coenzyme Q10 is a potent antioxidant that helps to generate energy within the cells. Research has shown that coenzyme Q10 supplementation can reduce fatigue levels and improve overall physical function in patients with chronic fatigue syndrome.

Magnesium is a vital mineral that plays a crucial role in energy production and neuromuscular function. Studies have shown that magnesium supplementation can improve fatigue levels and overall quality of life in patients with chronic fatigue syndrome.

According to statistics, up to 2.5 million Americans suffer from chronic fatigue syndrome, with the condition affecting more women than men. Additionally, studies have shown that people with chronic fatigue syndrome have lower levels of certain vitamins and minerals, including magnesium and coenzyme Q10.

In conclusion, if you are struggling with chronic fatigue syndrome, adding these supplements to your daily routine may help improve your symptoms and overall energy levels. As always, it is essential to consult with your healthcare provider before starting any new supplement regimen to ensure it is safe and effective for you.


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